Excessive Sweating Causes Social Embracement

Editor's Notes

1. Excessive sweating is a common problem, especially of the palms, armpits and soles. It can be distressing and can have a serious impact on your life.
2. Eccrine glands - Our bodies have two to four million sweat glands, most of which are eccrine glands. It is found in almost all regions of skin; their highest density is in the axillary region, on the palms of the hands, and on the soles of the feet. They produce (odorless) sweat that reaches the surface of the skin through coiled ducts (tubes). As sweat evaporates from the skin, the body cools, hence, their main function is thermoregulation Apocrine glands - these develop in areas of the body where there is a lot of hair, as well as the breasts. The apocrine glands in the breast secrete fat droplets into breast milk. The ones found in the ear help form earwax. Those found in the skin and eyelids are sweat glands. Most of the apocrine glands in the skin are found in the groin, the area around the nipples of the breast and in the armpits - they are scent glands and their secretions generally have an odor (smell). These scent glands become active during puberty and secrete a viscous fluid. They are responsible for a person’s "personal," occasionally unpleasant, odor. The unpleasant odor associated with axillary hyperhidrosis is osmidrosis and believed to be caused by interaction of secretions from the apocrine glands with microorganisms in the axilla and often related to hyperhidrosis.
3. Apocrine glands - these develop in areas of the body where there is a lot of hair, as well as the breasts. The apocrine glands in the breast secrete fat droplets into breast milk. The ones found in the ear help form earwax. Those found in the skin and eyelids are sweat glands. Most of the apocrine glands in the skin are found in the groin, the area around the nipples of the breast and in the armpits - they are scent glands and their secretions generally have an odor (smell). These scent glands become active during puberty and secrete a viscous fluid. They are responsible for a person’s "personal," occasionally unpleasant, odor. The unpleasant odor associated with axillary hyperhidrosis is osmidrosis and believed to be caused by interaction of secretions from the apocrine glands with microorganisms in the axilla and often related to hyperhidrosis.
4. Lastly, apoeccrine glands are sweat glands that become apparent between the ages of 8 and 14 years. They are functionally and pharmacologically distinct from apocrine glands and contribute heavily to overall axillary sweating. They develop during puberty from eccrine like precursor glands
5. Hyperhidrosis, means excessive sweating; sweating too much. sweating tend to start during a person's teenage years - their adolescence. The excessive sweating may be either localized (Focal) in specific parts of the body, or generalized (everywhere
6. ). Focal hyperhidrosis - when the excessive sweating is localized; affects (a)specific area(s). For example palmoplantar hyperhidrosis or acrohyperhidrosis is symptomatic sweating of primarily the hands or feet.
7. Generalized hyperhidrosis - when the excessive sweating affects the entire body. Hyperhidrosis may be congenital or an acquired trait. Congenital means you are born with it, while an acquired trait means you are not; the condition is acquired later in life after birth. Hyperhidrosis may be categorized as being the result of an underlying health condition, or with no apparent cause: primary (idiopathic) hyperhidrosis - there is no apparent cause. Idiopathic means "of unknown cause". In the majority of cases the hyperhidrosis is localized.
8. Secondary hyperhidrosis - the person sweats too much because of an underlying health condition, such as obesity, gout, menopause, a tumor, mercury poisoning, diabetes mellitus, or hyperthyroidism (overactive thyroid gland). It can also be caused by some medications. Generalized hyperhidrosis is more common among patients with secondary hyperhidrosis
9. Sweating is a physiological vital process. The basic distinction is made between two types of sweating: thermoregulatory and emotional sweating.
10. Emotional sweating The second type of sweating is emotional sweating. This
11. Although not a medically serious condition, excessive sweating can be distressing and embarrassing
12. Serves as a physical "feedback" signal in emotionally affecting sensory, cognitive, and behaviorally relevant processes. It maintains the trophic functions of the sensorly important palms and soles
13. The unpleasant odor associated with axillary hyperhidrosis is osmidrosis caused by interaction with microorganisms in the axilla and often related to hyperhidrosis.
14. . Only sweaty clothes that are not changed that may become smelly.)
15. It is used to assess the size of the surface area involved and is used primarily for assessing the area to be treated, but it does not give any indication on severity
16. The starch-iodine combination turns a dark blue color wherever there is excess sweat. Routine photography of the starch-iodine test areas can assist in the follow-up evaluation of patients
17. Avoid clothes that more easily show up sweat marks. As a rule, white and black colored clothes are less noticeable when wet than other colors
18. Avoid clothes that more easily show up sweat marks. As a rule, white and black colored clothes are less noticeable when wet than other colors
19. Wear loose clothing under the armpits.. Consider using dress shields (also known as armpit or sweat shields) to absorb excess sweat and protect delicate or expensive clothing.
20. For sweaty feet change your socks at least twice a day. Wear a different pair of shoes on alternate days. This allows them to dry fully. Buy shoes that are made of leather, canvas or mesh, rather than synthetic material. Avoid sport shoes or boots, as these are often less breathable than normal shoes are, so are more likely to keep the sweat
21. et Clinical Strength) contain the ingredient aluminum zirconium tricholorohydrex, but Secret Clinical Strength features a concentration that is 25 percent higher
22. (Note: there.
23. Mild axillary, palmar, and plantar hyperhidrosis should initially be treated with topical AC. If the patient fails to respond to AC therapy, BTX-A (axillae, palms, soles) and iontophoresis (palms, soles) should be the second-line therapy. In severe cases of axillary, palmar, and plantar hyperhidrosis , both BTX-A and topical AC are first-line therapy
24. Antiperspirants are considered the first line of treatment for excessive sweating of the underarms, hands, feet, and sometimes face
25. If you have armpit sweating: try using normal antiperspirants regularly
26. .. Clinical strength antiperspirants contain higher concentrations of active ingredients than “regular” strength over-the-counter antiperspirants (for example, both Secret and Secr
27. . Glutaraldehyde solution 2% as Cidex, is not as effective but less staining 10% dilution
28. In cases of gustatory sweating (in diabetes or Frey’s syndrome), 0.5% glycopyrrholate, an anticholinergic substance, may be applied topically
29. Research has shown that treating excessive sweating of the armpits, hands, feet, and face with onabotulinumtoxinA is safe and effective. Prevents calcium-dependent release of acetylcholine and produces a state of denervation at the neuromuscular junction and postganglionic sympathetic cholinergic nerves in the sweat glands. It is injected intradermally, and each injection produces an area of anhydrosis approximately 1.2 cm in diameter. Reportedly, results in anhydrosis lasting 4-12 months. Injections of botulinum toxin must be repeated at varying intervals to maintain long-term results. There have been no treatment-related serious adverse events reported in clinical trials of BoNT-A for hyperhidrosis, even after repeated treatments. The side effects, if any, are typically mild and transient.
30. An initial dose of 100U of BTX-A per palm has been shown to be effective but may need to be increased to 150U per palm depending on patient response . Recommended dose is 1.5 to 2 U/cm2 with a mean dose of 100 U per palm.
31. An initial dose of 150U of BTX-A per sole has been shown to be effective but may need to be increased to 200U per sole depending on patient response and surface area involvement. The recommended dose is 1.5 to 2 U/cm2 with a mean dose of 150U per sole. I
32. BTX-A provides significant reduction in the severity of truncal CH. Every patient appeared to benefit from treatment with 100 to 500U of BTX-A. It is recommended to use the Minor iodine-starch test to guide the range of injections. However, using BTX-A injection to treat patients with severe CH at multiple sites is limited
33. Prevents calcium-dependent release of acetylcholine and produces a state of denervation at the neuromuscular junction and postganglionic sympathetic cholinergic nerves in the sweat glands
34. . Recommended dose is 1 U/cm2 (3–4U or every 1.5–2 cm to a total of 50 to 100 U/ axilla depending on patient response and surface area of involvement
35. Botox intradermal injection of 1U /cm2 with an average dose of 40U/patient is effective therapy
36. water iontophoresis is the method of choice for the initial treatment of palmar and plantar hyperhidrosis because of its low side effect profile and effectiveness. Sometimes, tap water in certain geographic locations may be too "soft" for iontophoresis to work. That is, it doesn't contain many minerals or electrolytes (tiny particles that help the electric current travel through the water and into the skin). Adding about a teaspoon of baking soda to the trays of water will take care of this
37. water iontophoresis is the method of choice for the initial treatment of palmar and plantar hyperhidrosis because of its low side effect profile and effectiveness. Sometimes, tap water in certain geographic locations may be too "soft" for iontophoresis to work. That is, it doesn't contain many minerals or electrolytes (tiny particles that help the electric current travel through the water and into the skin). Adding about a teaspoon of baking soda to the trays of water will take care of this
38. a prescription medicine for hyperhidrosis called an anticholinergic (for example, Robinul; generic name, glycopyrrolate) may be crushed and added to the water. The hands or feet are immersed into water or moist electrodes are applied. The assumed mechanism of action is a reversible disruption of the ion transport in the secretory tangle of the sweat glands, possibly owing to accumulation of protons in the sweat gland ducts. Reversible disruption of the ion transport in the secretory tangle of the sweat glands, possibly owing to accumulation of protons in the sweat gland ducts
39. but is very time consuming; initially it should be administered at least three times per week. A maintenance treatment is then usually required once every 1-4 weeks to keep symptoms away. Each treatment session lasts 20-40 minutes. Most people see an improvement after 6-10 sessions.
40. However
41. The most commonly used medications for managing excessive sweating are anticholingerics. Oxybutynin (brand name Ditropan) is one that has shown promise,although it has important side effects, which include drowsiness, visual symptoms and dryness in the mouth and other mucous membranes. A time release version of the drug is also available (Ditropan XL), with purportedly reduced effectiveness. Glycopyrrolate (Robinul) is another drug used on an off-label basis. The drug seems to be almost as effective as oxybutynin and has similar side-effects. Other anticholinergic agents that have tried to include propantheline bromide (Probanthine) and benztropine (Cogentin